Fetal-type Glycogen Phosphorylase (FGP)Expression in Intestinal Metaplasia as a High Risk Factor of the Development of Gastric Carcinoma
نویسندگان
چکیده
It has been reported that an enzyme-glycogen phosphorylase [EC 2.4.1.1] histochemical re‐ action is observed in differentiated hepatic or muscular tissues and in some proliferating tis‐ sues including fetus and carcinoma [1,2]. In the human stomach, a phosphorylase reaction appears in the undifferentiated gastric epithelium at the midpoint of fetal life, and is not de‐ tected in gastric epithelium after birth.
منابع مشابه
مقایسه موسین موجود در سلولهای مخاط معده بیماران مبتلا به گاستریت هلیکوباکترپیلوری با افراد طبیعی
ABSTRACT Gastric cancer (GC) is one of the most common cancers in the world. Despite some improvement in the treatment of this type of cancer, the 5-year survival rate has been already remained low. Therefore further exploration of biological features and causes of gastric cancer is needed to reduce its occurrence. In sequential changes from superficial gastritis to dysplasia and cance...
متن کاملSquamous Cell Differentiation in Metastatic Papillary Thyroid Carcinoma: Metaplastic
Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1) and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...
متن کاملGastric Intestinal Metaplasia: An Intermediate Precancerous Lesion in the Cascade of Gastric Carcinogenesis.
Gastric intestinal metaplasia, an intermediate lesion in the development of intestinal-type gastric cancer, is observed in the milieu of long standing non-atrophic gastritis and atrophic gastritis. Most patients with intestinal metaplasia remain asymptomatic unless cobalamin deficiency occurs secondary to loss of glands (that produce intrinsic factor and acid). Genetic events that predispose to...
متن کاملLI-cadherin: a marker of gastric metaplasia and neoplasia.
BACKGROUND Intestinal metaplasia is considered a risk factor for the development of gastric adenocarcinomas of the intestinal type and is found in approximately 20% of gastric biopsies. Conventional histology only detects advanced stages of intestinal metaplasia. AIMS To study expression of the enterocyte specific adhesion molecule liver-intestinal (LI)-cadherin in intestinal metaplasia as we...
متن کاملبررسی شیوع هلیکوباکتر پیلوری در گاستریت، بافتشناسی و متاپلاری رودهای و رابطه آن با سن و جنس ـ مطالعه آماری 576 بیمار مبتلا به دیسپپسی بدون زخم در بخش آندوسکوپی مرکز آموزشی درمانی فیروزگر
ABSTRACT Helicobacter pylori has a centeral role in the pathogensis of chronic Active gastritis. Infection usually occures during childhood and last for a lifetime. Infectious is a worldwide phenomen but its prevalence is varied. Chronic (Atrophic) gastritis and intestinal metaplasia was accepted as a precursor of intestinal type gastric Carcinoma. Now more searches in the world doing ab...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره شماره
صفحات -
تاریخ انتشار 2017